You're probably thinking the same thing I thought: "What?!" How does that even make sense? Well I didn't know either until I read this very informative, give-you-a-bad-image-in-your-head article on a molecule called lucanthone.
Lucanthone is supposed to "sensitize tumor cells to radiation and chemotherapy by inhibiting DNA repair" (Balaseshan). Makes sense, right?
This drug is currently in Phase 2 trials, where they will be enrolling 140 patients to test it's affects. After this phase, it will enter a "maintenance phase of lucanthone (active arm) or placebo (control arm) administered with TMZ on days 1-5 of a 28-day cycle for 6 cycles" (Balaseshan).
How it works: Lucanthone crosses the blood-brain barrier and acts upon different cycling cells.
Well, I am not an expert on the subject. But I encourage you to read this article (I was kidding when I said it would put a bad image in your head; totally kidding).
The link is as follows:
http://www.istockanalyst.com/finance/story/5926355/spectrum-pharma-sppi-launches-primary-brain-tumor-treatment-trial
Cited:
Balaseshan. "Spectrum Pharma (SPPI) Launches Primary Brain Tumor Treatment Trial." iStockAnalyst. N.p., 03 Jul 2012. Web. 16 Aug 2012. <http://www.istockanalyst.com/finance/story/5926355/spectrum-pharma-sppi-launches-primary-brain-tumor-treatment-trial>
This drug is currently in Phase 2 trials, where they will be enrolling 140 patients to test it's affects. After this phase, it will enter a "maintenance phase of lucanthone (active arm) or placebo (control arm) administered with TMZ on days 1-5 of a 28-day cycle for 6 cycles" (Balaseshan).
How it works: Lucanthone crosses the blood-brain barrier and acts upon different cycling cells.
Well, I am not an expert on the subject. But I encourage you to read this article (I was kidding when I said it would put a bad image in your head; totally kidding).
The link is as follows:
http://www.istockanalyst.com/finance/story/5926355/spectrum-pharma-sppi-launches-primary-brain-tumor-treatment-trial
Cited:
Balaseshan. "Spectrum Pharma (SPPI) Launches Primary Brain Tumor Treatment Trial." iStockAnalyst. N.p., 03 Jul 2012. Web. 16 Aug 2012. <http://www.istockanalyst.com/finance/story/5926355/spectrum-pharma-sppi-launches-primary-brain-tumor-treatment-trial>
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